DEX 410R Wiring Questions

[syac25]

I just purchased the Durango DEX410R (my first kit after owning an RTR) and I'm about to wire it up. Being a 4wd vehicle, I'm a bit concerned about the lack of space for the ESC and receiver. I have 2 Q's:

1. Can/should I place the ESC wires over the drive shaft to wire the motor? I'm concerned that if I run them underneath they'll rub against the drive shaft, or worse hit the spur gear.

2. Can/should I mount the receiver (Spektrum Dx3s) on it's side, as opposed to flat. I don't seem to have enough room to lay it flat.

Thanks!