Nosram Evil Power ESC with mind of it's own..

[eda]

I am running a Nosram Evil Power ESC with a Speed Passion 10.5 motor. Almost every race night the ESC will lose it's settings, e.g. motor goes in to reverse after changing a battery pack or suddenly needs 20 notches of throttle trim. Not good on the start line!
Anyone else with the same problem? Instructions seem to suggest compatability issues with some 2.4GHz receivers - I run Spektrum 2.4GHz so maybe that's the problem?