SANWA all the way, I upgraded from the DX4S to the M12 (on offer at Hobbyking £280 instead of £425) and the difference is night and day, its like the first time you watch an HD TV, going back to DX4S on another car is like playing VRC pro with a ton of lag on the internet connection.
If budget allows stretch to the MT4S it has the same response time as the M12 which are both faster than the MT4 and DX4S but the S is smaller lighter TX compared the behemoth M12 which is very top heavy.