Losi everytime mate, there is no real comparisson in my eyes. I have owned quite a few 1/8's over the last few years and evertime I tried another chassis, after about 3 months I always went back to a Losi, and I am not on my own there either....
The Durango is gorgeous to look at and looks awesome on the track, but can be a pig to work on and maintain, whereas the Losi can be stripped, cleaned and rebuilt in a matter of a few hours. Losi's also get better with age and seem to perform better once the 'slop' has kicked in.
The EU is a much better car for the UK than the standard 2.0 and will be a more rewarding drive and own than the Durango, but having said that, the 408 was one of the few cars that I didnt own, so I cant speak for experience.
Other things to take into consideration is how many Losi's will be at your local tracks compared to the Durango's? This is a major factor when looking for support, set up help and of course spares if needed....
Yes there are other chassis like the Mugen (pricey), MP9 (even more pricey), Hobao, GX, Agama etc. but if you want consistency on the track go for Losi everytime
