It's more to do with the overall weight distribution.
If the corner weights are the same then the buggy will handle very similarly in all layouts.
The bigest difference is when the weight is spread out wide of the centre line, the further out the more it will encourage the car to roll around .... good for generating grip in low traction conditions, bad for fast direction changes.
As a rule of thumb the buggy will feel more nimble with the weight closest to the centreline.
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