Yes that would work. 2250kv would still be a bit overpower for racing (great for bashing) and 40c is kinda high especially with 2250. for 4s you need a min of 25C constant. the difference between 25C & 40c will be a noticeable amount of power and the 40c will be 15-30Deg F hotter. if you must keep that motor you can definitely go 25C to cool things down and believe me you will still have plenty of power. (25C will be lighter, cheaper and cooler). I'd only go 40c+ if you were running a 1700-1900kv motor. I realize if you are getting the hobby wing brand ESC your are probably getting the 2250 that is on their website too for a great price and they do not have alot of 1900-2050 motors. I did find this combo though:
http://www.hobbypartz.com/07e-c-combo-m3a.html
I run a 1900kv 210amp (no fans needed) and batteries that are between 25-35C with a burst of 32-45C (depending on the pack). In the summer we regularly race in temperatures of 35-40Dec Cel and up so temps are of big concern to us around here. Our tracks tend to be tighter than European tracks, But even if I were to run on bigger tracks i'd go up to 2050kv and keep a lower C rating to balance temps. In September we are running 5hr enduro race with our Ebuggy. Last year's 4hr and we learned many heat related lessons with various packs of different C ratings, weights and capacities.
But, the final answer is yes it will work and the car will be extremely fast. And totally fine if you run in cold areas and/or you are just bashing. If you race hard long races or in hot regions and get some high temps, remember this post and you'll know why.