Hi bigfella,
Gearing wise - presuming it's a sintered rotor - go for 22/78 or 23/81
Setup wise, 5 or 10g lead weights in the corner pods of the chassis (front and rear), weight underneath the rear shock tower - approx 28g or run the Ghea brass bulkheads
5-10g lead in the front nose can help - or again, run a brass front bulkhead and since you're running Lipo, a thin slab of lead under the battery (approx 110g) will help.
In all, up weight will be approx 1525g.
a Jconcepts front wing can help flying a little nose down and a K-factory front shock tower is a must if you hit things hard like me
Suspension wise - 30 deg caster blocks (optional) on the front and springing damping is up to you.
For over here on high grip astro, the blue front springs with silver rears are a safe bet (35Wt front / 30wt rear) or drop 5wt and a spring grade possibly since the lipo will be a bit lighter than nimhs or if you want to help generate more grip.
Can't think of too much more to say - you won't go too far wrong - the weight in the chassis corner pods and behind the rear shock tower really help.
HTH