You also need to be aware of the oil content.
The 16% you refer to is the nitro content which as Mark says, will affect your engine's performance and you will need to adjust your carb settings to maintain optimum temps etc.
But the fuel also contains the lubricating oil and the amount (and type) of oil in the fuel will also have a big effect on the engine cooling and running performance.
Changing manufacturer (assuming both are reputable) won't be a problem but changing either the nitro or the oil content is likely to necessitate re-setting of the carb.
You can do an awful lot of damage very quickly with an engine that is running too lean - Here speaks the voice of experience
As a general pointer - also don't forget that the engine will lean out as the fuel tank runs dry - so an engine that is optimum at the beginning of a run may begin to become over-lean towards the end of the run - it is always safest to set as rich as possible so that it will (just) accelerate cleanly from idle without 4-stroking or 'fluffing' on a full tank.
HTH